GENETIC DEFICIENCY OF GLYCOGEN SYNTHASE KINASE-3BETA CORRECTS DIABETES IN MOUSE MODELS OF INSULIN RESISTANCE.

Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance.

Despite treatment with agents that enhance Attendant Jacket beta-cell function and insulin action, reduction in beta-cell mass is relentless in patients with insulin resistance and type 2 diabetes mellitus.Insulin resistance is characterized by impaired signaling through the insulin/insulin receptor/insulin receptor substrate/PI-3K/Akt pathway, lea

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Femoral and tibial cementless fixation neither increases blood loss nor impedes early functional recovery: A randomized controlled trial

BackgroundWhether cementless fixation on femoral and tibial components increases blood loss during total knee arthroplasty (TKA) is unclear.The purpose of this randomized controlled trial was to compare blood loss and early functional recovery between patients who underwent cementless or cemented TKA.MethodsBetween November 2021 and April 2022, six

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Explaining and analyzing the ways of communication and dialogue between religions in Imami jurisprudential thought

Interfaith communication and the conversation of followers of religions with each other is one of the most important necessities in the present age.Utilizing the knowledge of jurisprudence as a science expressing the practical duty of those in charge has a great role in explaining the ways of this communication and dialogue.Among the jurisprudentia

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